Exploring the 2025 BioSpace Hotbed Maps: Key Life Sciences Regions in the U.S.
BioSpace has unveiled its 2025 Hotbed Maps, illustrating prominent life sciences regions across the United States. Originating from the first map featuring Biotech Bay in 1989, the initiative has expanded to cover nine major areas, reflecting significant transformations in the biopharma sector over the decades.
Top Life Sciences Hotspots
California: Biotech Bay and Biotech Beach
California has consistently been a leader in life sciences innovation. Biotech Bay encompasses the San Francisco Bay Area, including Menlo Park and Palo Alto, while Biotech Beach covers the San Diego and Los Angeles regions. Although these areas face economic pressures, optimism rises around future employment opportunities in the biotechnology sector.
Genetown: A Hub for Cell and Gene Therapy
Genetown, incorporating Boston and Cambridge in Massachusetts, is renowned for its contributions to cell and gene therapies. The region is poised for growth, bolstered by a newly expanded tax incentive program expected to spur job creation over the next decade, making the job market in this sector particularly promising.

Pharm Country: An Ecosystem of Innovation
The Pharm Country region, which covers Connecticut, New York, New Jersey, Pennsylvania, and Rhode Island, is distinguished by its vast array of research universities and prominent pharmaceutical companies, including AbbVie and Regeneron. This area serves as a nurturing ground for numerous small biotech firms, enhancing its reputation as a key player in biopharma research and development.

BioMidwest: Manufacturing Powerhouse
BioMidwest, encompassing the states of Illinois, Indiana, Iowa, Michigan, Minnesota, Missouri, Nebraska, Ohio, and Wisconsin, hosts a variety of manufacturing facilities and biotech enterprises. A notable player, Eli Lilly, continues to invest in this region, notably through the development of new manufacturing sites and the recently announced Lilly Medicine Foundry, aimed at supporting R&D initiatives.

Other Notable Hotbed Regions
Additional noteworthy life sciences hubs recognized in the 2025 BioSpace Hotbed Maps include:
- Bio NC – Encompassing the Research Triangle Park in North Carolina.
- BioForest – Covering Oregon and Washington.
- BioCapital – Including Delaware, Maryland, Virginia, and Washington, D.C.
- Lone Star Bio – Representing Texas.
Get Involved
Organizations seeking representation on the Hotbed Maps can find more information here.