Look at the “Sunday Night Football” table. Sunday’s nightcap will be in upstate New York, where the Buffalo Bills (9-2) will host the San Francisco 49ers (5-6).
San Francisco has had its ups and downs all season, but it appears to be suffering from a Super Bowl hangover after the 49ers’ loss to the Green Bay Packers. Sure, Brock Purdy didn’t play, but the 49ers didn’t look like a contender to win the NFC.
Buffalo is still going strong despite a week off after suffering their first loss of the season to the Kansas City Chiefs and officially declaring themselves Super Bowl contenders. Now the Bills have a chance to beat last season’s Super Bowl opponent in front of their home crowd.
Bills vs. 49ers odds, money line, over/under
The Chiefs are the favorites to beat the Ravens, according to BetMGM’s NFL odds. Interested in this game? Check out our expert-picked best bets for all NFL games this week.
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Spread: Bills (-7) Moneyline: Bills (-350); 49ers (+260)Over/Under: 44.5
NFL Week 13 Odds, Predictions, Picks
Lions vs. Bears | Cowboys vs. Giants | Packers vs. Dolphins | Chiefs vs. Raiders | Falcons vs. Chargers | Bengals vs. Steelers | Jaguars vs. Texans | Vikings vs. Cardinals | Patriots vs. Colts | Jets vs. Seahawks | Commanders vs. Titans | Panthers vs. Buccaneers | Saints vs. Rams | Ravens vs. Eagles | Bills vs. 49ers |Broncos vs. Browns
Lorenzo Reyes: Bills 26, 49ers 14
Buffalo has a bye and the 49ers are in great shape, so it’s hard to support them at this position. Especially since the Bills are on a roll. Either way, I’m going to wait until later in the week to see what’s going on with Brock Purdy and the rest of the guys to see who’s eligible.
Tyler Dragon: Bills 27, 49ers 24
The 49ers’ impact player has battled injuries all season. Brock Purdy is scheduled to return this week. Will Purdy’s return change things for Buffalo? Yes, but that doesn’t lead to victory.
Richard Morin: Bills 28, 49ers 20
It’s hard to see the 49ers pulling this off. Buffalo is on a roll right now, and I can’t imagine losing at home.
Jordan Mendoza: Bills 33, 49ers 24
Brock Purdy’s situation is something to keep an eye on, but it will largely determine whether or not this game is a close one. Buffalo had another impressive performance, scoring at least 30 points in five straight games.
(This story has been updated to change the video.)
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